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I've never had these problems, and I usually have Photoshop going with Maya, Zbrush and a bunch of other crap running in the background. How ancient is the machine you're trying to run this on?
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Now that is odd, since on my 3.0ghz P4 witrh 2 gig of ram, nothing else open, quick strokes in Photoshop always come out like this for me:
I gave up trying to figure out what the hell my issue was and got OpenCanvas with no similiar issues. Feels nice, and I love the rotating canvas.