Originally Posted by sprunghunt
there is a system in windows called "windows ink"(wisptis.exe) which detects pen strokes on a tablet PC. It's the thing that plays a little "splash" animation beneath the cursor whenever you click with your pen. However it just gets in the way of using a wacom. You can remove it but it's not easy.
Theres another way around it, its still quite annoying, but it works.
"The culprit is wisptis.exe. It can cause all kinds of problems with Max\Wacom\Zbrush etc. When it is triggered by an app it is still completely invisible, both in processes and in services. And if you remove it, it is automatically reinstalled by the OS. (Nice one MS) So here is how to get rid of it. (Warning this is unlikely to harm your system but hey things happen:)
1. Navigate to C:\windows\system32\wisptis.exe
2. Right click and go to Security..click Advanced
3. Go to the Owner tab
4. Click Edit
5. Add your login as a new user
6. Take ownership of the file.
7. Click “Change permissions”
8. Add your login account if you don’t see it.
9. Then edit the setting for the account and give your self full control.
10. Now you need to rename the wisptis.exe to something else and replace it with a empty text file of the same name.
11. Now when Windows call this file nothing happens and because the file is there it is not restored"
Found it here.